This is a sad and familiar story. I had an immunological gene panel done a number of years back to see if I was a candidate for some of the new gene therapies for Common Variable Immune Deficiency (CVID). I was not, but they found a NOD2 gene mutation that can cause Crohn's Disease. I don't have Crohn's (yet as I've been told) but I do have a thing called Yao Syndrome that falls under the same gene mutation(s) for Crohn's and causes an auto-inflammatory disease. I had "just" IBS and a host of unexplained inflammatory processes that couldn't be caused by CVID. Many folks also have auto-immune which may or many not be specifically related, but part of the immune system becoming dis-regulated and common. Environmental toxins and pathogens are know to cause gene mutations, and these can also be carried down leaving subsequent generations more susceptible to disease processes. I know that with each viral infection I've had over the years, the worse I got. This specific gene mutation that I have (that caused Crohn's disease) was thought to be cause by the Black Plague, and then passed down. What will happen to all the future generation with COVID? We as a society are not ready and barely have the will to handle previous diseases.
Compelling. Your Dad’s story is now your fateful journey. I’m sorry your son has repercussions from a double exposure. May things slowly resolve. We’re part of a minority group that in and of itself blows my mind. We’re like outsiders looking in or perhaps, more accurate, on the inside peering out - we can’t afford to expose our vulnerable hyper reactive immune systems to more depleting hits. As a retired HCW, I never thought looking in the rear view mirror would evoke such sadness and yes, grieving the reverence of something woven through my impassioned heart & soul. I think of this often, feeling the ‘powers that be’ had my back, our backs, our collective best interests as priority. Mega hospital systems have removed integrity & critical thinking from medicine. It’s the antithesis of irony. At my age, it’s hard to imagine where we’re headed without feeling an anger so unfamiliar to who I’ve always been. I worry about my adult kids, grandkid’s futures. I too, had a late Feb ‘20 undocumented presumptive Covid hit. My husband, daughter as well. Nothing compared to it’s wrath. Prior, I’ve lived with degenerative joint disease hEDS, Sjogrens, the usual suspects crossing over the complicated AI spectrum. COVID awakened these entities FULL TIME. TKA 12 yrs ago at 53 currently needing 3 more joint surgeries but won’t expose - let me rephrase - *cannot chance the risks of recuperating from major surgery WITH COVID. For 3yrs now since March ‘20, I live in 24/7 365 pain and dysfunction. Literally feel 20 yrs older. It’s nothing short of all encompassing depressing but offers a challenge to seek gratitude in the face of darkness. There’s so many far worse I can’t imagine. I don’t talk about it much because it’s exhausting. We are committed to live withOUT COVID because the opposite is not an option for both my husband and I. He’s 75 severe asthma remission cancer almost 4 yrs now. It takes all of who we are to remain steadfast in very scaled down lives especially when family members literally scream we need to seek help because we still insist on non negotiable science based mitigations for methodical, strategic visits. I. Can’t. Even.
YES Reverence lost, grieving ever present. Happy Monday In February in the Midwest :o Grateful you are writing, sharing, caring, it helps ALL of us in this twilight zone bubble. Take care. x
This is a sad and familiar story. I had an immunological gene panel done a number of years back to see if I was a candidate for some of the new gene therapies for Common Variable Immune Deficiency (CVID). I was not, but they found a NOD2 gene mutation that can cause Crohn's Disease. I don't have Crohn's (yet as I've been told) but I do have a thing called Yao Syndrome that falls under the same gene mutation(s) for Crohn's and causes an auto-inflammatory disease. I had "just" IBS and a host of unexplained inflammatory processes that couldn't be caused by CVID. Many folks also have auto-immune which may or many not be specifically related, but part of the immune system becoming dis-regulated and common. Environmental toxins and pathogens are know to cause gene mutations, and these can also be carried down leaving subsequent generations more susceptible to disease processes. I know that with each viral infection I've had over the years, the worse I got. This specific gene mutation that I have (that caused Crohn's disease) was thought to be cause by the Black Plague, and then passed down. What will happen to all the future generation with COVID? We as a society are not ready and barely have the will to handle previous diseases.
It seems we're trending backwards in medicine and most folks are a bit too comfortable with this.
Compelling. Your Dad’s story is now your fateful journey. I’m sorry your son has repercussions from a double exposure. May things slowly resolve. We’re part of a minority group that in and of itself blows my mind. We’re like outsiders looking in or perhaps, more accurate, on the inside peering out - we can’t afford to expose our vulnerable hyper reactive immune systems to more depleting hits. As a retired HCW, I never thought looking in the rear view mirror would evoke such sadness and yes, grieving the reverence of something woven through my impassioned heart & soul. I think of this often, feeling the ‘powers that be’ had my back, our backs, our collective best interests as priority. Mega hospital systems have removed integrity & critical thinking from medicine. It’s the antithesis of irony. At my age, it’s hard to imagine where we’re headed without feeling an anger so unfamiliar to who I’ve always been. I worry about my adult kids, grandkid’s futures. I too, had a late Feb ‘20 undocumented presumptive Covid hit. My husband, daughter as well. Nothing compared to it’s wrath. Prior, I’ve lived with degenerative joint disease hEDS, Sjogrens, the usual suspects crossing over the complicated AI spectrum. COVID awakened these entities FULL TIME. TKA 12 yrs ago at 53 currently needing 3 more joint surgeries but won’t expose - let me rephrase - *cannot chance the risks of recuperating from major surgery WITH COVID. For 3yrs now since March ‘20, I live in 24/7 365 pain and dysfunction. Literally feel 20 yrs older. It’s nothing short of all encompassing depressing but offers a challenge to seek gratitude in the face of darkness. There’s so many far worse I can’t imagine. I don’t talk about it much because it’s exhausting. We are committed to live withOUT COVID because the opposite is not an option for both my husband and I. He’s 75 severe asthma remission cancer almost 4 yrs now. It takes all of who we are to remain steadfast in very scaled down lives especially when family members literally scream we need to seek help because we still insist on non negotiable science based mitigations for methodical, strategic visits. I. Can’t. Even.
YES Reverence lost, grieving ever present. Happy Monday In February in the Midwest :o Grateful you are writing, sharing, caring, it helps ALL of us in this twilight zone bubble. Take care. x
Solidarity. This felt much less daunting when we were all in it together, but we know the importance of maintaining a science-based approach.